Basically, every superhuman Earthling in the Marvel Universe - be they mutant, Inhuman, super-soldier or Hulk - can trace their powers back to the original genetic tampering performed by the Celestials. But while humanity wasn't blessed with the long life and incredible powers of the Eternals, their DNA carries the potential for incredible acts of mutation. The result of that experimentation was three species of life - the genetically superior Eternals, the powerful but monstrous Deviants and boring old humans. As they're wont to do, the Celestials hoped to introduce newer, more powerful and more genetically diverse forms of life to the universe. In the mythology of the Marvel Universe, the godlike cosmic beings known as the Celestials came to Earth and meddled with the DNA of mankind's prehistoric ancestors. While that may seem strange given the lack of deep ties between the two franchises, it's also perfectly plausible. The Eternals and Mutants There's a persistent (albeit dubiously sourced) rumor online that Marvel's The Eternals will wind up serving as a backdoor introduction for the X-Men in the MCU. In his quest to tamp down the spread of life, Thanos may have instead created something new and wonderful. This five-year gap may have been created specifically so that the long-term effects of that gamma burst could play out and mutants could start spontaneously appearing across the globe. With Earth being exposed to that much gamma radiation (the same substance that transformed Bruce Banner into Hulk, mind you), is it possible Thanos inadvertently spawned a whole new generation of mutants? It's also worth remembering that the "present-day" MCU is currently set in 2023 - five years after Thanos' snap. The Avengers were able to track down Thanos by pinpointing a similar gamma burst in another part of the universe. Early in the film, we learn that the Infinity Gauntlet unleashed a massive burst of gamma energy when Thanos used it to wipe out half of all life. Bearing that in mind, Endgame may have just given the fledgling mutant race the catalyst it needed to grow. But thanks to the rise of nuclear technology in the 20th century, the mutant race began to explode in numbers. Historically in the Marvel Universe, mutants were an extremely rare offshoot of humans. Those genetic changes cause the child to manifest the mutant gene, transforming them from Homo sapiens to Homo superior. Consider this - mutants are created when the parent's DNA is mutated through exposure to radiation, cosmic rays or some other unstable substance. Avengers: Endgame and the Gamma Effect It's entirely possible Avengers: Endgame already started the process of introducing mutants into the MCU.
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